Gayther Laboratory

 
gayther

The research of Simon Gayther, PhD, focuses on four areas: identification of genetic variants that confer susceptibility to hormonal cancers, particularly ovarian cancer, using next-generation sequencing and genotyping technologies; relating germ-linegenetic variation to functional targets throughout the human genome, specifically epigenetic and regulatory profiles enriched in the noncoding genome, and the susceptibility genes that drive cancer development; cell biology modeling of cancer to establish functional mechanisms underlying cancer initiation and development; and clinical translation of this research program, specifically establishing a genetic basis for risk prediction and prevention of cancer, and the identification of novel clinical biomarkers associated with early-stage pathogenesis of disease.

 

 

Groups

  Functional Genomics and GWAS

Functional Genomics and GWAS

  Cell biology and molecular carcinogenesis group

Cell biology and molecular carcinogenesis group

  Genetic Epidemiology and Variant Discovery

Genetic Epidemiology and Variant Discovery